Psychiatric disorders in clinical genetics II: Individualizing recurrence risks

Jehannine C. Austin, Christina G.S. Palmer, Beth Rosen-Sheidley, Patricia Mc Carthy Veach, Elizabeth Gettig, Holly L. Peay

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations

Abstract

This is the second article of a two-part professional development series on genetic counseling for personal and family histories of psychiatric disorders. It is based on an Educational Breakout Session presented by The Psychiatric Special Interest Group of the National Society of Genetic Counselors at the 2006 Annual Education Conference. While the first article in this two part series dealt with addressing family histories of psychiatric disorders in clinical practice, the following discussion deals with the generation and provision of individualized recurrence risks for psychiatric disorders, based on empiric risk data. We present four cases that illustrate important components of and process for generating individualized risk assessment for family histories of psychiatric disorders.

Original languageEnglish (US)
Pages (from-to)18-29
Number of pages12
JournalJournal of Genetic Counseling
Volume17
Issue number1
DOIs
StatePublished - Feb 2008

Bibliographical note

Funding Information:
Acknowledgements We would like to thank the members of the Psychiatric SIG, the individuals from whom we have learned through clinical contact, and all who attended the 2006 Educational Breakout Session from which this article was developed. JA is supported by the Canadian Institutes of Health Research (NET-54013), the Michael Smith Foundation for Health Research, and the BC Mental Health and Addictions Services. HP is supported by the Intramural Research Program of the National Human Genome Research Institute, National Institutes of Health.

Keywords

  • Autism
  • Bipolar disorder
  • Empiric risk
  • Genetic counseling
  • Mental illness
  • Psychiatric disorders
  • Schizophrenia

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