Pseudomembranous colitis after itraconazole therapy

Adrienne J. Nguyen; Douglas B. Nelson; Joseph R Thurn

doi:10.1016/s0002-9270(99)00300-7

Pseudomembranous colitis after itraconazole therapy

Adrienne J. Nguyen
, Douglas B. Nelson
, Joseph R Thurn

Medicine - Veteran's Administration Medical Center

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A 53-yr-old man was admitted with new onset of abdominal pain and nonbloody diarrhea 1 month after exposure to the antifungal agent itraconazole. Flexible sigmoidoscopy demonstrated the presence of pseudomembranes, and subsequent evaluation excluded other causes of diarrhea. Disruption of the resident fungal flora of the colon by itraconazole is proposed as the mechanism by which this patient developed pseudomembranous colitis. This association has not previously been reported.

Original language	English (US)
Pages (from-to)	1971-1973
Number of pages	3
Journal	American Journal of Gastroenterology
Volume	94
Issue number	7
DOIs	https://doi.org/10.1016/s0002-9270(99)00300-7
State	Published - Jul 1999

Publisher link

10.1016/s0002-9270(99)00300-7

Find It

Find It at U of M Libraries

Cite this

@article{f2608c6207b3440aaf5ed8f5f9fb086d,

title = "Pseudomembranous colitis after itraconazole therapy",

abstract = "A 53-yr-old man was admitted with new onset of abdominal pain and nonbloody diarrhea 1 month after exposure to the antifungal agent itraconazole. Flexible sigmoidoscopy demonstrated the presence of pseudomembranes, and subsequent evaluation excluded other causes of diarrhea. Disruption of the resident fungal flora of the colon by itraconazole is proposed as the mechanism by which this patient developed pseudomembranous colitis. This association has not previously been reported.",

author = "Nguyen, \{Adrienne J.\} and Nelson, \{Douglas B.\} and Thurn, \{Joseph R\}",

year = "1999",

month = jul,

doi = "10.1016/s0002-9270(99)00300-7",

language = "English (US)",

volume = "94",

pages = "1971--1973",

journal = "American Journal of Gastroenterology",

issn = "0002-9270",

publisher = "Wolters Kluwer Health",

number = "7",

}

TY - JOUR

T1 - Pseudomembranous colitis after itraconazole therapy

AU - Nguyen, Adrienne J.

AU - Nelson, Douglas B.

AU - Thurn, Joseph R

PY - 1999/7

Y1 - 1999/7

N2 - A 53-yr-old man was admitted with new onset of abdominal pain and nonbloody diarrhea 1 month after exposure to the antifungal agent itraconazole. Flexible sigmoidoscopy demonstrated the presence of pseudomembranes, and subsequent evaluation excluded other causes of diarrhea. Disruption of the resident fungal flora of the colon by itraconazole is proposed as the mechanism by which this patient developed pseudomembranous colitis. This association has not previously been reported.

AB - A 53-yr-old man was admitted with new onset of abdominal pain and nonbloody diarrhea 1 month after exposure to the antifungal agent itraconazole. Flexible sigmoidoscopy demonstrated the presence of pseudomembranes, and subsequent evaluation excluded other causes of diarrhea. Disruption of the resident fungal flora of the colon by itraconazole is proposed as the mechanism by which this patient developed pseudomembranous colitis. This association has not previously been reported.

UR - https://www.scopus.com/pages/publications/0033051034

UR - https://www.scopus.com/pages/publications/0033051034#tab=citedBy

U2 - 10.1016/s0002-9270(99)00300-7

DO - 10.1016/s0002-9270(99)00300-7

M3 - Article

C2 - 10406273

AN - SCOPUS:0033051034

SN - 0002-9270

VL - 94

SP - 1971

EP - 1973

JO - American Journal of Gastroenterology

JF - American Journal of Gastroenterology

IS - 7

ER -

Pseudomembranous colitis after itraconazole therapy

Abstract

Publisher link

Find It

Other files and links

Fingerprint

Cite this