Proton therapy for central nervous system tumors in children

Matthew M. Ladra, Shannon M. MacDonald, Stephanie A. Terezakis

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Proton therapy is a form of particle therapy with physical properties that provide a superior dose distribution compared to photons. The ability to spare healthy, developing tissues from low dose radiation with proton therapy is well known. The capability to decrease radiation exposure for children has been lauded as an important advance in pediatric cancer care, particularly for central nervous system (CNS) tumors. Favorable clinical outcomes have been reported and justify the increased cost and burden of this therapy. In this review, we summarize the current literature for proton therapy for pediatric CNS malignancies, with a focus on clinical outcomes to date.

Original languageEnglish (US)
Article numbere27046
JournalPediatric Blood and Cancer
Issue number7
StatePublished - Jul 2018
Externally publishedYes


  • brain tumors
  • protons
  • radiation

PubMed: MeSH publication types

  • Journal Article
  • Review


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