TY - JOUR
T1 - Protective effect of Cynodon dactylon against STZ induced hepatic injury in rats
AU - Singh, Santosh Kumar
AU - Rai, Prashant Kumar
AU - Jaiswal, Dolly
AU - Rai, Devendra K.
AU - Sherma, Bechan
AU - Watal, Geeta
PY - 2008/12
Y1 - 2008/12
N2 - The present study was designed to investigate the hepatoprotective effect of aqueous extract of Cynodon dactylon, widely used in India as a traditional treatment for diabetes mellitus. Male Albino Wistar rats (180-220 g) were administered with streptozotocin (STZ, 50 mg/kg) intraperitoneally to induce experimental diabetes. Alkaline phosphatase (ALKP), serum glutamate oxaioacetate transaminase (SG0T), serum glutamate pyruvate transaminase (SGPT), croatinine (CRTN) and total protein (TP), urine sugar (US) and total haemoglobin (Hb) were estimated at the beginning and after 14 days of treatment. Daily oral administration of aqueous extract of Cynodon dactylon suspended in distilled water at 500 mg/kg dose almost normalized various biochemical parameters. This suggests that Cynodon dactylon can be used as a hepatoprotective agent.
AB - The present study was designed to investigate the hepatoprotective effect of aqueous extract of Cynodon dactylon, widely used in India as a traditional treatment for diabetes mellitus. Male Albino Wistar rats (180-220 g) were administered with streptozotocin (STZ, 50 mg/kg) intraperitoneally to induce experimental diabetes. Alkaline phosphatase (ALKP), serum glutamate oxaioacetate transaminase (SG0T), serum glutamate pyruvate transaminase (SGPT), croatinine (CRTN) and total protein (TP), urine sugar (US) and total haemoglobin (Hb) were estimated at the beginning and after 14 days of treatment. Daily oral administration of aqueous extract of Cynodon dactylon suspended in distilled water at 500 mg/kg dose almost normalized various biochemical parameters. This suggests that Cynodon dactylon can be used as a hepatoprotective agent.
KW - Alkaline phosphatase
KW - Creatinine
KW - Cynodon dectylon
KW - Serum glutamate pyruwate transminase
KW - Serum glutanate oxaloacietate transminase
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M3 - Article
AN - SCOPUS:65549106082
SN - 0972-4397
VL - 8
SP - 195
EP - 199
JO - Journal of Ecophysiology and Occupational Health
JF - Journal of Ecophysiology and Occupational Health
IS - 3-4
ER -
