Prostaglandins E and F in the house cricket and other insects

Michael P. Murtaugh, David L. Denlinger

Research output: Contribution to journalArticlepeer-review

61 Scopus citations


Prostaglandin E (PGE1 and PGE2) and prostaglandin F (PGF) are widely distributed in insects belonging to seven species representing six orders. Whole body concentrations range from 0.2 to 16 pg/mg protein. PGE and PGF are found in muscle but are not abundant in testicular tissue. In the house cricket, Acheta domesticus (L.), high prostaglandin levels in the testes and the female spermatheca are reduced in the presence of the prostaglandin synthesis inhibitors aspirin, acetaminophen and indomethacin. An interaction of the prostaglandins with cyclic GMP and cyclic AMP in cricket tissues was not observed using these inhibitors. The house cricket appears to be a model for studying prostaglandin function in insects.

Original languageEnglish (US)
Pages (from-to)599-603
Number of pages5
JournalInsect Biochemistry
Issue number6
StatePublished - 1982

Bibliographical note

Funding Information:
Acknowledgements We thankP . J. A. DAVIESa nd A. L. STEINER for their critical readinga nd discussiono f the manuscript.T his research was supported by grant #780059f5r om the CompetitivRe esearchG rantsOffice, U.S. Departmenotf Agricultureb,y a GraduateF ellowship from the Ohio State University Graduate School to M.P.M. and by a Sigma Xi Grant-in-Aid-of-Researtcoh M.P.M.


  • Acheta domesticus
  • Prostaglandins
  • cricket
  • reproduction


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