Proline-catalyzed simple and efficient synthesis of 1,8-dioxo- decahydroacridines in aqueous ethanol medium

K. Venkatesan; Suresh S. Pujari; Kumar V. Srinivasan

doi:10.1080/00397910802044306

Proline-catalyzed simple and efficient synthesis of 1,8-dioxo- decahydroacridines in aqueous ethanol medium

K. Venkatesan, Suresh S. Pujari, Kumar V. Srinivasan

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

Proline-catalyzed synthesis of 1,8-dioxo-decahydroacridines is achieved via one-pot, three-component condensation of aromatic aldehydes, cyclic diketone, and aryl amines in aqueous ethanol medium. This method offers the advantages of proceeding in neutral and mild conditions, giving high to excellent yields of acridines with easy workup procedure.

Original language	English (US)
Pages (from-to)	228-241
Number of pages	14
Journal	Synthetic Communications
Volume	39
Issue number	2
DOIs	https://doi.org/10.1080/00397910802044306
State	Published - Jan 2009
Externally published	Yes

Bibliographical note

Funding Information:
K.V. thanks University Grants Commission, New Delhi, for providing a research fellowship.

Keywords

1,8-dioxodecahydroacridines
Aqueous media
One-pot MCR
Proline

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10.1080/00397910802044306

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author = "K. Venkatesan and Pujari, {Suresh S.} and Srinivasan, {Kumar V.}",

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AU - Pujari, Suresh S.

AU - Srinivasan, Kumar V.

N1 - Funding Information: K.V. thanks University Grants Commission, New Delhi, for providing a research fellowship.

PY - 2009/1

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N2 - Proline-catalyzed synthesis of 1,8-dioxo-decahydroacridines is achieved via one-pot, three-component condensation of aromatic aldehydes, cyclic diketone, and aryl amines in aqueous ethanol medium. This method offers the advantages of proceeding in neutral and mild conditions, giving high to excellent yields of acridines with easy workup procedure.

AB - Proline-catalyzed synthesis of 1,8-dioxo-decahydroacridines is achieved via one-pot, three-component condensation of aromatic aldehydes, cyclic diketone, and aryl amines in aqueous ethanol medium. This method offers the advantages of proceeding in neutral and mild conditions, giving high to excellent yields of acridines with easy workup procedure.

KW - 1,8-dioxodecahydroacridines

KW - Aqueous media

KW - One-pot MCR

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ER -

Proline-catalyzed simple and efficient synthesis of 1,8-dioxo- decahydroacridines in aqueous ethanol medium

Abstract

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Keywords

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