Proliferative enteropathy

Research output: Chapter in Book/Report/Conference proceedingChapter

21 Scopus citations


This chapter provides in-depth coverage of proliferative enteropathy (PE) including relevance, potential public health significance, epidemiology, pathogenesis, clinical signs, lesions, diagnosis, immunity, and prevention and control. PE, also known as ileitis, is an infectious disease caused by the obligate intracellular bacterium Lawsonia intracellularis. Three clinically different forms of PE are observed most commonly: acute, chronic, and subclinical. The clinical diagnosis of PE has been historically based on clinical and pathological characteristics of the L. intracellularis infection. The differential diagnosis for clinical cases of PE varies with the particular form of the disease. Improved farm hygiene measures will reliably reduce levels of PE. Rigorous washing and cleaning of feces from all parts of pig pens, facilities, boots, and equipment on both single-site and multisite farms, as well as insect and rodent control, are likely to be more effective at reduction of PE than reliance on slatted floors and sunken pits for feces removal.

Original languageEnglish (US)
Title of host publicationDiseases of Swine
Number of pages14
ISBN (Electronic)9781119350927
ISBN (Print)9781119350859
StatePublished - Mar 29 2019

Bibliographical note

Publisher Copyright:
© 2019 John Wiley & Sons, Inc.


  • Differential diagnosis
  • Farm hygiene measures
  • Lawsonia intracellularis
  • Pigs
  • Proliferative enteropathy


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