Proliferative enteritis associated with Lawsonia intracellularis in a Japanese macaque (Macaca fuscata)

Maud Lafortune; James F.X. Wellehan; Elliott R. Jacobson; J. Mitchell Troutman; Connie J. Gebhart; Margaret S. Thompson

doi:10.1638/03-080

Proliferative enteritis associated with Lawsonia intracellularis in a Japanese macaque (Macaca fuscata)

Maud Lafortune, James F.X. Wellehan, Elliott R. Jacobson, J. Mitchell Troutman, Connie J. Gebhart, Margaret S. Thompson

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

A 2.5-yr-old, intact male Japanese macaque (Macaca fuscata) was observed to have a thickened ileum during exploratory laparotomy. Lawsonia intracellularis-associated proliferative enteritis was diagnosed using histopathology (Warthin-Starry stain), immunohistochemistry, and polymerase chain reaction analysis of the ileal biopsy. The animal developed transient diarrhea and severe hypoproteinemia 16 days after surgery but recovered with intensive treatment using azithromycin. Given the fact that very specific tests are required for identifying this organism, L. intracellularis may be underdiagnosed in nonhuman primates.

Original language	English (US)
Pages (from-to)	549-552
Number of pages	4
Journal	Journal of Zoo and Wildlife Medicine
Volume	35
Issue number	4
DOIs	https://doi.org/10.1638/03-080
State	Published - Dec 2004

Keywords

Diarrhea
Japanese macaque
Lawsonia intracellularis
Macaca fuscata
Nonhuman primate
Proliferative enteropathy

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10.1638/03-080

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abstract = "A 2.5-yr-old, intact male Japanese macaque (Macaca fuscata) was observed to have a thickened ileum during exploratory laparotomy. Lawsonia intracellularis-associated proliferative enteritis was diagnosed using histopathology (Warthin-Starry stain), immunohistochemistry, and polymerase chain reaction analysis of the ileal biopsy. The animal developed transient diarrhea and severe hypoproteinemia 16 days after surgery but recovered with intensive treatment using azithromycin. Given the fact that very specific tests are required for identifying this organism, L. intracellularis may be underdiagnosed in nonhuman primates.",

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AU - Lafortune, Maud

AU - Wellehan, James F.X.

AU - Jacobson, Elliott R.

AU - Troutman, J. Mitchell

AU - Gebhart, Connie J.

AU - Thompson, Margaret S.

PY - 2004/12

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AB - A 2.5-yr-old, intact male Japanese macaque (Macaca fuscata) was observed to have a thickened ileum during exploratory laparotomy. Lawsonia intracellularis-associated proliferative enteritis was diagnosed using histopathology (Warthin-Starry stain), immunohistochemistry, and polymerase chain reaction analysis of the ileal biopsy. The animal developed transient diarrhea and severe hypoproteinemia 16 days after surgery but recovered with intensive treatment using azithromycin. Given the fact that very specific tests are required for identifying this organism, L. intracellularis may be underdiagnosed in nonhuman primates.

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KW - Lawsonia intracellularis

KW - Macaca fuscata

KW - Nonhuman primate

KW - Proliferative enteropathy

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Proliferative enteritis associated with Lawsonia intracellularis in a Japanese macaque (Macaca fuscata)

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