Prolactin response to beta-endorphin in man

S. C. Schulz, R. Wagner, D. P. van Kammen, A. D. Rogol, G. C. Davis, R. J. Wyatt, D. Pickar, W. E. Bunney, C. H. Li

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Beta endorphin was administered intravenously to six medication-free schizophrenic patients under placebo-controlled conditions. Serum prolactin (PRL) and growth hormone (GH) concentrations were measured for 90 minutes after infusion. Prolactin was significantly increased following beta-endorphin infusion compared to placebo infusions. Growth hormone levels were not affected by beta-endorphin. The implications of the PRL response in schizophrenic patients await further study.

Original languageEnglish (US)
Pages (from-to)1735-1741
Number of pages7
JournalLife Sciences
Issue number19
StatePublished - 1980


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