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Progress in pathogenesis studies of spinocerebellar ataxia type 1
Christopher J. Cummings
,
Harry T. Orr
, Huda Y. Zoghbi
Laboratory Medicine and Pathology
Genetics Mechanisms of Cancer
Research output
:
Contribution to journal
›
Article
›
peer-review
40
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Scopus citations
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Keyphrases
Aggregate Formation
7%
Ataxia
21%
Ataxin-1
100%
Brain Regions
7%
Brainstem nuclei
7%
CAG Repeat
7%
CAG Tract
7%
Cell Abnormalities
7%
Cell Behavior
7%
Cell Pathology
7%
Cell-type Specificity
7%
Cerebellar Purkinje Cell
14%
Chaperone
14%
Disease Progression
7%
Following Model
7%
Glutamine
14%
HeLa Cells
14%
Hippocampal Plasticity
7%
Immunolocalization Studies
7%
Inclusion Formation
7%
Inherited Disorders
7%
Learning Impairment
7%
Leucine-rich
7%
Molecular Chaperone
7%
Motor Impairment
7%
Neurodegeneration
7%
Neurodegenerative Diseases
7%
Neuronal Pathology
7%
Novel Functions
14%
Nuclear Inclusion
21%
Nuclear Localization
7%
Nuclear Localization Signal
7%
Nuclear Proteins
7%
Overexpression
7%
Pathogenesis Studies
100%
Polyglutamine Tract
7%
Protein Aggregation
7%
Protein Misfolding
14%
Protein-protein Interaction
7%
Purkinje Cell
14%
Self-association
7%
Specificity Protein 1
14%
Spinocerebellar Ataxia
100%
Spinocerebellar Tracts
7%
Transgenic Mice
28%
Two-line
7%
Ubiquitin
7%
Neuroscience
Ataxia
23%
Ataxin
7%
Ataxin 1
100%
Brain Region
7%
Brainstem
7%
CAG Repeat
7%
Cell Function
7%
Cell Specificity
7%
Chaperone
23%
Glutamine
15%
Learning Disabilities
7%
Leucine
7%
Nerve Cell Degeneration
7%
Neurodegenerative Disorder
7%
Nuclear Localization Signal
7%
Nuclear Protein
7%
Nucleus
15%
Polyglutamine
7%
Proteasome
23%
Protein Aggregation
7%
Protein Interaction
7%
Protein Misfolding
15%
Proteolysis
7%
Purkinje Cell
30%
Spinocerebellar Ataxia
100%
Spinocerebellar Tract
7%
Stereotypic Movement Disorder
7%
Synaptic Plasticity
7%
Ubiquitin
7%