TY - JOUR
T1 - Prognostic Importance of Premature Beats Following Myocardial Infarction
T2 - Experience in the Coronary Drug Project
AU - Blackburn, Henry
PY - 1973/3/5
Y1 - 1973/3/5
N2 - Two hundred thirty-five men among 2,035 survivors of myocardial infarction (11.5%) had one or more ventricular premature beats (VPB) in their resting base-line electrocardiogram. During a three-year follow-up period, deaths were about twice as frequent in those with any VPB (21.7%) as in those with none (11.4%) among the placebo-treated patients in the nationwide Coronary Drug Project. Excess long-term risk of death, including sudden death, was associated with the frequency of VPB, with VPB in pairs or runs, and possibly with early-cycle VPB. The excess risk with these VPB characteristics was independent of the risk associated with other electrocardiographic and clinical characteristics.
AB - Two hundred thirty-five men among 2,035 survivors of myocardial infarction (11.5%) had one or more ventricular premature beats (VPB) in their resting base-line electrocardiogram. During a three-year follow-up period, deaths were about twice as frequent in those with any VPB (21.7%) as in those with none (11.4%) among the placebo-treated patients in the nationwide Coronary Drug Project. Excess long-term risk of death, including sudden death, was associated with the frequency of VPB, with VPB in pairs or runs, and possibly with early-cycle VPB. The excess risk with these VPB characteristics was independent of the risk associated with other electrocardiographic and clinical characteristics.
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U2 - 10.1001/jama.1973.03220100016005
DO - 10.1001/jama.1973.03220100016005
M3 - Article
C2 - 4119817
AN - SCOPUS:0015914731
SN - 0098-7484
VL - 223
SP - 1116
EP - 1124
JO - JAMA: The Journal of the American Medical Association
JF - JAMA: The Journal of the American Medical Association
IS - 10
ER -
