Prognostic Importance of Premature Beats Following Myocardial Infarction: Experience in the Coronary Drug Project

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Abstract

Two hundred thirty-five men among 2,035 survivors of myocardial infarction (11.5%) had one or more ventricular premature beats (VPB) in their resting base-line electrocardiogram. During a three-year follow-up period, deaths were about twice as frequent in those with any VPB (21.7%) as in those with none (11.4%) among the placebo-treated patients in the nationwide Coronary Drug Project. Excess long-term risk of death, including sudden death, was associated with the frequency of VPB, with VPB in pairs or runs, and possibly with early-cycle VPB. The excess risk with these VPB characteristics was independent of the risk associated with other electrocardiographic and clinical characteristics.

Original languageEnglish (US)
Pages (from-to)1116-1124
Number of pages9
JournalJAMA: The Journal of the American Medical Association
Volume223
Issue number10
DOIs
StatePublished - Mar 5 1973

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