Lasting achlorhydria was produced in rats by irradiation of the exposed stomach. Gastric pH determination in the living animal correlates well with the degree of impairment of gastric acid secretion induced by irradiation. Rats treated in this way provide a good experimental model comparable to an animal with total gastrectomy but without the disadvantage of an interrupted gut.
|Original language||English (US)|
|Number of pages||3|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Jul 1969|
Bibliographical noteFunding Information:
Supported by the John Hartford Foundation and by the National Institute of Arthritis and Metabolic Disease Research Grant No. AM 10976-01. 7 1969 131 3 737 739