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Pro-oxidant and cytotoxic effects of circulating heme
Viktória Jeney
, József Balla
, Akihiro Yachie
, Zsuzsa Varga
,
Gregory M. Vercellotti
, John W. Eaton
, György Balla
Medicine - Hematology, Oncology, Transplant
Transplant and Cellular Therapy
Research output
:
Contribution to journal
›
Article
›
peer-review
566
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Scopus citations
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Keyphrases
Heme
100%
Cytotoxic Effect
100%
Pro-oxidant Effect
100%
Low-density Lipoprotein
66%
Heme oxygenase-1 (HO-1)
55%
Hemoglobin
44%
Methemoglobin
33%
Oxidative Modification
22%
Ferritin
22%
Oxidized Low-density Lipoprotein (ox-LDL)
22%
Leukocytes
11%
Knock-in Mouse Model
11%
Cytotoxicity
11%
Central Nervous System
11%
Spectral Analysis
11%
Endothelium
11%
Vascular Endothelium
11%
Reactive Oxygen Species
11%
Renal Failure
11%
Free Heme
11%
Lipid Hydroperoxides
11%
Transgenic Knock-out
11%
Atherogenesis
11%
Fatty Acid Hydroperoxides
11%
Toxic Side Effects
11%
Children's Plasma
11%
Cytolysis
11%
Free Hemoglobin
11%
Lethal Concentration
11%
Intravascular Hemolysis
11%
Oxidized Form
11%
Human Patients
11%
Hemorrhagic Injury
11%
Pharmacology, Toxicology and Pharmaceutical Science
Oxidizing Agent
100%
Heme
100%
Cytotoxicity
100%
Low Density Lipoprotein
60%
Heme Oxygenase 1
50%
Iron
30%
Methemoglobin
30%
Ferritin
20%
Oxidized Low Density Lipoprotein
20%
Knockout Mouse
10%
Fatty Acid
10%
Kidney Failure
10%
Atherogenesis
10%
Hydroperoxide
10%
Intravascular Hemolysis
10%
Lipid Hydroperoxide
10%
Side Effect
10%
Biochemistry, Genetics and Molecular Biology
Pro-Oxidant
100%
Cytotoxicity
100%
Low-Density Lipoprotein
100%
Heme Oxygenase
62%
Blood Plasma
50%
Methemoglobin
37%
Ferritin
25%
Lipid
12%
Enzyme
12%
Leukocyte
12%
Transgenics
12%
Knockout Mouse
12%
Hemoglobin Blood Level
12%
Cytolysis
12%
Deficiency
12%