Principles of cryopreservation

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Biospecimens are important reagents that are used to diagnose disease, monitor response to treatment and help in the development and testing of new therapies to treat human disease. In order to provide these critical functions, biospecimens need to maintain their requisite biological properties between the time that they are collected and when they are used. It is common for biospecimens to be frozen to preserve those critical biological properties. The purpose of this chapter is to describe our scientific understanding behind the freezing, storage and thawing processes that take place during cryopreservation and the manner by which these processes can preserve or damage the sample. Practical hints for applying scientific principles to daily biobanking practice are also included.

Original languageEnglish (US)
Title of host publicationBiobanking of Human Biospecimens
Subtitle of host publicationPrinciples and Practice
PublisherSpringer International Publishing
Pages1-21
Number of pages21
ISBN (Electronic)9783319551203
ISBN (Print)9783319551180
DOIs
StatePublished - Jul 6 2017

Fingerprint

Cryopreservation
Freezing
Therapeutics

Keywords

  • Biospecimens
  • Cooling rate
  • Cryopreservation
  • Storage temperature
  • Warming rate

Cite this

Hubel, A., & Skubitz, A. P. (2017). Principles of cryopreservation. In Biobanking of Human Biospecimens: Principles and Practice (pp. 1-21). Springer International Publishing. https://doi.org/10.1007/978-3-319-55120-3_1

Principles of cryopreservation. / Hubel, Allison; Skubitz, Amy P.

Biobanking of Human Biospecimens: Principles and Practice. Springer International Publishing, 2017. p. 1-21.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hubel, A & Skubitz, AP 2017, Principles of cryopreservation. in Biobanking of Human Biospecimens: Principles and Practice. Springer International Publishing, pp. 1-21. https://doi.org/10.1007/978-3-319-55120-3_1
Hubel A, Skubitz AP. Principles of cryopreservation. In Biobanking of Human Biospecimens: Principles and Practice. Springer International Publishing. 2017. p. 1-21 https://doi.org/10.1007/978-3-319-55120-3_1
Hubel, Allison ; Skubitz, Amy P. / Principles of cryopreservation. Biobanking of Human Biospecimens: Principles and Practice. Springer International Publishing, 2017. pp. 1-21
@inbook{a68309150614469f90e6c440451e8271,
title = "Principles of cryopreservation",
abstract = "Biospecimens are important reagents that are used to diagnose disease, monitor response to treatment and help in the development and testing of new therapies to treat human disease. In order to provide these critical functions, biospecimens need to maintain their requisite biological properties between the time that they are collected and when they are used. It is common for biospecimens to be frozen to preserve those critical biological properties. The purpose of this chapter is to describe our scientific understanding behind the freezing, storage and thawing processes that take place during cryopreservation and the manner by which these processes can preserve or damage the sample. Practical hints for applying scientific principles to daily biobanking practice are also included.",
keywords = "Biospecimens, Cooling rate, Cryopreservation, Storage temperature, Warming rate",
author = "Allison Hubel and Skubitz, {Amy P}",
year = "2017",
month = "7",
day = "6",
doi = "10.1007/978-3-319-55120-3_1",
language = "English (US)",
isbn = "9783319551180",
pages = "1--21",
booktitle = "Biobanking of Human Biospecimens",
publisher = "Springer International Publishing",

}

TY - CHAP

T1 - Principles of cryopreservation

AU - Hubel, Allison

AU - Skubitz, Amy P

PY - 2017/7/6

Y1 - 2017/7/6

N2 - Biospecimens are important reagents that are used to diagnose disease, monitor response to treatment and help in the development and testing of new therapies to treat human disease. In order to provide these critical functions, biospecimens need to maintain their requisite biological properties between the time that they are collected and when they are used. It is common for biospecimens to be frozen to preserve those critical biological properties. The purpose of this chapter is to describe our scientific understanding behind the freezing, storage and thawing processes that take place during cryopreservation and the manner by which these processes can preserve or damage the sample. Practical hints for applying scientific principles to daily biobanking practice are also included.

AB - Biospecimens are important reagents that are used to diagnose disease, monitor response to treatment and help in the development and testing of new therapies to treat human disease. In order to provide these critical functions, biospecimens need to maintain their requisite biological properties between the time that they are collected and when they are used. It is common for biospecimens to be frozen to preserve those critical biological properties. The purpose of this chapter is to describe our scientific understanding behind the freezing, storage and thawing processes that take place during cryopreservation and the manner by which these processes can preserve or damage the sample. Practical hints for applying scientific principles to daily biobanking practice are also included.

KW - Biospecimens

KW - Cooling rate

KW - Cryopreservation

KW - Storage temperature

KW - Warming rate

UR - http://www.scopus.com/inward/record.url?scp=85033346847&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85033346847&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-55120-3_1

DO - 10.1007/978-3-319-55120-3_1

M3 - Chapter

SN - 9783319551180

SP - 1

EP - 21

BT - Biobanking of Human Biospecimens

PB - Springer International Publishing

ER -