Abstract
This chapter is an introduction to the biology of cancer and the subsequent rationale for therapeutics used in the treatment of cancer. The biological features of cancer are presented with an emphasis on general principles and how neoplastic alterations inform treatment. Further, the key features of cancer presentation in the clinic and the objectives of cancer chemotherapy are discussed.
| Original language | English (US) |
|---|---|
| Title of host publication | Brody's Human Pharmacology |
| Publisher | Elsevier |
| Pages | 623-631 |
| Number of pages | 9 |
| ISBN (Electronic) | 9780323846738 |
| ISBN (Print) | 9780323846745 |
| DOIs | |
| State | Published - Jan 1 2024 |
Bibliographical note
Publisher Copyright:© 2025 Elsevier Inc. All rights reserved.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- adjuvant therapy
- biomarker
- carcinomas
- chemotherapy
- drug combinations
- drug resistance
- heterogeneity
- immunotherapy
- leukemias
- lymphomas
- metastasis
- neoadjuvant therapy
- oncogene
- precision medicine
- sarcomas
- stage
- targeted therapy
- tumor microenvironment
- tumor suppressor gene
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