Primary Optic Nerve Sheath Meningioma in Children

Hui Bae Harold Lee, James A. Garrity, John D Cameron, Diego Strianese, Giulio Bonavolontà, James R. Patrinely

Research output: Contribution to journalReview article

38 Citations (Scopus)

Abstract

Primary optic nerve sheath meningioma represents a proliferation of meningothelial cap cells of the arachnoid villi within the optic nerve sheath. Patients younger than 20 years of age make up less than 5% of all cases of pediatric primary optic nerve meningiomas. Histopathologically, the most common subtypes in children are transitional (54%) and meningotheliomatous (38%). This tumor has been called aggressive in the pediatric population, with surgical excision recommended. However, the tumor may spread intraorbitally, intracranially, or intraocularly after subtotal surgical resection. Recent studies examined the use of fractionated, stereotactic radiation in children with this tumor; however, follow-up is limited. Neurofibromatosis type 2 is concomitantly diagnosed in 28% of patients with pediatric primary optic nerve sheath meningioma. There have been no known deaths attributed primarily to this tumor.

Original languageEnglish (US)
Pages (from-to)543-558
Number of pages16
JournalSurvey of Ophthalmology
Volume53
Issue number6
DOIs
StatePublished - Nov 1 2008

Fingerprint

Meningioma
Optic Nerve
Pediatrics
Neoplasms
Neurofibromatosis 2
Arachnoid
Radiation
Population

Keywords

  • children
  • meningioma
  • optic nerve
  • orbit
  • pediatric
  • sheath
  • tumor

Cite this

Harold Lee, H. B., Garrity, J. A., Cameron, J. D., Strianese, D., Bonavolontà, G., & Patrinely, J. R. (2008). Primary Optic Nerve Sheath Meningioma in Children. Survey of Ophthalmology, 53(6), 543-558. https://doi.org/10.1016/j.survophthal.2008.08.022

Primary Optic Nerve Sheath Meningioma in Children. / Harold Lee, Hui Bae; Garrity, James A.; Cameron, John D; Strianese, Diego; Bonavolontà, Giulio; Patrinely, James R.

In: Survey of Ophthalmology, Vol. 53, No. 6, 01.11.2008, p. 543-558.

Research output: Contribution to journalReview article

Harold Lee, HB, Garrity, JA, Cameron, JD, Strianese, D, Bonavolontà, G & Patrinely, JR 2008, 'Primary Optic Nerve Sheath Meningioma in Children', Survey of Ophthalmology, vol. 53, no. 6, pp. 543-558. https://doi.org/10.1016/j.survophthal.2008.08.022
Harold Lee HB, Garrity JA, Cameron JD, Strianese D, Bonavolontà G, Patrinely JR. Primary Optic Nerve Sheath Meningioma in Children. Survey of Ophthalmology. 2008 Nov 1;53(6):543-558. https://doi.org/10.1016/j.survophthal.2008.08.022
Harold Lee, Hui Bae ; Garrity, James A. ; Cameron, John D ; Strianese, Diego ; Bonavolontà, Giulio ; Patrinely, James R. / Primary Optic Nerve Sheath Meningioma in Children. In: Survey of Ophthalmology. 2008 ; Vol. 53, No. 6. pp. 543-558.
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