Primary Infection with Zidovudine-Resistant HIV

P. Hermans; S. Sprecher; N. Clumeck; Bernard Masquelier; Emmanuelle Lemoigne; Isabelle Pellegrin; Danielle Douard; Boris Sandler; Herve J.a. Fleury; Alejo Erice; Henry H. Balfour

doi:10.1056/NEJM199310073291514

Primary Infection with Zidovudine-Resistant HIV

P. Hermans
, S. Sprecher
, N. Clumeck
, Bernard Masquelier
, Emmanuelle Lemoigne
, Isabelle Pellegrin
, Danielle Douard
, Boris Sandler
, Herve J.a. Fleury
, Alejo Erice
, Henry H. Balfour

Laboratory Medicine and Pathology

Research output: Contribution to journal › Letter › peer-review

23 Scopus citations

Abstract

To the Editor: Erice et al. (April 22 issue)¹ described a patient with symptomatic human immunodeficiency virus type 1 (HIV-1) infection who had a primary infection with a virus resistant to zidovudine. We report the case of a homosexual man in whom clinical symptoms of acute HIV-1 infection developed in May 1992; tests for HIV-1 antibodies were positive in July 1992. His most recent negative HIV-1 test was in November 1991. We studied the presence of genotypic mutations at codons 215 and 74 of the HIV pol gene – those associated with reduced sensitivity to zidovudine and didanosine, respectively. We…

Original language	English (US)
Pages (from-to)	1123-1124
Number of pages	2
Journal	New England Journal of Medicine
Volume	329
Issue number	15
DOIs	https://doi.org/10.1056/NEJM199310073291514
State	Published - Oct 7 1993

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@article{825120480c6b4084b718b54e9937f435,

title = "Primary Infection with Zidovudine-Resistant HIV",

abstract = "To the Editor: Erice et al. (April 22 issue)1 described a patient with symptomatic human immunodeficiency virus type 1 (HIV-1) infection who had a primary infection with a virus resistant to zidovudine. We report the case of a homosexual man in whom clinical symptoms of acute HIV-1 infection developed in May 1992; tests for HIV-1 antibodies were positive in July 1992. His most recent negative HIV-1 test was in November 1991. We studied the presence of genotypic mutations at codons 215 and 74 of the HIV pol gene – those associated with reduced sensitivity to zidovudine and didanosine, respectively. We…",

author = "P. Hermans and S. Sprecher and N. Clumeck and Bernard Masquelier and Emmanuelle Lemoigne and Isabelle Pellegrin and Danielle Douard and Boris Sandler and Fleury, \{Herve J.a.\} and Alejo Erice and Balfour, \{Henry H.\}",

year = "1993",

month = oct,

day = "7",

doi = "10.1056/NEJM199310073291514",

language = "English (US)",

volume = "329",

pages = "1123--1124",

journal = "New England Journal of Medicine",

issn = "0028-4793",

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TY - JOUR

T1 - Primary Infection with Zidovudine-Resistant HIV

AU - Hermans, P.

AU - Sprecher, S.

AU - Clumeck, N.

AU - Masquelier, Bernard

AU - Lemoigne, Emmanuelle

AU - Pellegrin, Isabelle

AU - Douard, Danielle

AU - Sandler, Boris

AU - Fleury, Herve J.a.

AU - Erice, Alejo

AU - Balfour, Henry H.

PY - 1993/10/7

Y1 - 1993/10/7

N2 - To the Editor: Erice et al. (April 22 issue)1 described a patient with symptomatic human immunodeficiency virus type 1 (HIV-1) infection who had a primary infection with a virus resistant to zidovudine. We report the case of a homosexual man in whom clinical symptoms of acute HIV-1 infection developed in May 1992; tests for HIV-1 antibodies were positive in July 1992. His most recent negative HIV-1 test was in November 1991. We studied the presence of genotypic mutations at codons 215 and 74 of the HIV pol gene – those associated with reduced sensitivity to zidovudine and didanosine, respectively. We…

AB - To the Editor: Erice et al. (April 22 issue)1 described a patient with symptomatic human immunodeficiency virus type 1 (HIV-1) infection who had a primary infection with a virus resistant to zidovudine. We report the case of a homosexual man in whom clinical symptoms of acute HIV-1 infection developed in May 1992; tests for HIV-1 antibodies were positive in July 1992. His most recent negative HIV-1 test was in November 1991. We studied the presence of genotypic mutations at codons 215 and 74 of the HIV pol gene – those associated with reduced sensitivity to zidovudine and didanosine, respectively. We…

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UR - https://www.scopus.com/pages/publications/0027432106#tab=citedBy

U2 - 10.1056/NEJM199310073291514

DO - 10.1056/NEJM199310073291514

M3 - Letter

C2 - 8371739

AN - SCOPUS:0027432106

SN - 0028-4793

VL - 329

SP - 1123

EP - 1124

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 15

ER -

Primary Infection with Zidovudine-Resistant HIV

Abstract

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