Primary B-cell lymphoma with histologic features of a T-cell neoplasm

Nerea G. Landa, Brian D. Zelickson, Paul J. Kurtin, R. K. Winkelmann

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


A 58-year-old white man had dermatomyositis and primary cutaneous B-cell lymphoma. The cutaneous lymphoma was evidenced by a noduloulcerative disease of the lower extremities. Histologic results resembled a T-cell process with a diffuse, superficial infiltrate composed of small- and medium-sized lymphocytes with angioinvasion and epidermotropism. The infiltrate extended into the deep dermis and panniculus with scattered large lymphocytes and necrosis. With the help of gene-rearrangement analysis and immunophenotyping, the true B-cell lineage was discovered. The importance of gene-rearrangement analysis and immunophenotyping in the diagnosis of cutaneous lymphoma is emphasized.

Original languageEnglish (US)
Pages (from-to)288-292
Number of pages5
JournalJournal of the American Academy of Dermatology
Issue number2
StatePublished - Jan 1 1992
Externally publishedYes


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