Primary and Secondary Chemoprevention of Malignant Melanoma

Jessica Mounessa, Talayesa Buntinx-Krieg, Rosie Qin, Cory A. Dunnick, Robert P. Dellavalle

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

The incidence of malignant melanoma (MM) continues to rise in the United States. While sun protection and full body skin examinations remain the mainstay of preventative care, chemoprevention of the deadly disease has become an increasingly popular field of study. In this focused review, we discuss current findings and analyze the risks and benefits of various agents investigated for the primary and secondary chemoprevention of MM. Such agents include topical retinoids, vitamins, and supplements, Polypodium leucotomas extracts, non-steroidal anti-inflammatory agents (NSAIDs), statins, sunscreens, and field therapy with topical imiquimod for primary and secondary chemoprevention. We further identify a need for expanded high quality human research on the topic.

Original languageEnglish (US)
Pages (from-to)625-634
Number of pages10
JournalAmerican Journal of Clinical Dermatology
Volume17
Issue number6
DOIs
StatePublished - Dec 1 2016
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2016, Springer International Publishing Switzerland (Outside the USA).

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