TY - JOUR
T1 - Primary and secondary amenorrhea associated with spironolactone therapy in chronic liver disease
AU - Potter, Carol
AU - Willis, Dale
AU - Sharp, Harvey L.
AU - Schwarzenberg, Sarah Jane
PY - 1992/7
Y1 - 1992/7
N2 - Women with severe liver disease often have amenorrhea that resolves as liver disease abates. We describe three patients with mild to moderate chronic liver disease and amenorrhea. In each case amenorrhea resolved when spironolactone therapy was discontinued. We suggest that spironolactone, an androgen inhibitor, may also cause reversible amenorrhea.
AB - Women with severe liver disease often have amenorrhea that resolves as liver disease abates. We describe three patients with mild to moderate chronic liver disease and amenorrhea. In each case amenorrhea resolved when spironolactone therapy was discontinued. We suggest that spironolactone, an androgen inhibitor, may also cause reversible amenorrhea.
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U2 - 10.1016/S0022-3476(05)82562-4
DO - 10.1016/S0022-3476(05)82562-4
M3 - Article
C2 - 1625072
AN - SCOPUS:0026751708
VL - 121
SP - 141
EP - 143
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 1
ER -