Prevention of acute pulmonary edema during isolated perfusion for 24 hours

L. H. Toledo Pereyra, W. F. Northrup, E. W. Humphrey, J. S. Najarian

Research output: Contribution to journalArticlepeer-review

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Fifty nine canine lungs were perfused with cryoprecipitated plasma, silica gel fraction, or modified silica gel fraction (MSGF) at different perfusate pressures for periods up to 24 h under hypothermic conditions. High perfusate pressures accounted for all poor perfusion results. The use of MSGF at a low perfusate pressure protected all the lungs from the appearance of pulmonary edema during perfusion, and the morphology was consistently maintained for 24 hours.

Original languageEnglish (US)
Pages (from-to)554-559
Number of pages6
Issue number4
StatePublished - 1975

Bibliographical note

Funding Information:
Supported by Public Health Service grant 5-PO2-AM13083.


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