Fifty nine canine lungs were perfused with cryoprecipitated plasma, silica gel fraction, or modified silica gel fraction (MSGF) at different perfusate pressures for periods up to 24 h under hypothermic conditions. High perfusate pressures accounted for all poor perfusion results. The use of MSGF at a low perfusate pressure protected all the lungs from the appearance of pulmonary edema during perfusion, and the morphology was consistently maintained for 24 hours.
Bibliographical noteFunding Information:
Supported by Public Health Service grant 5-PO2-AM13083.