Preventing and managing cardiometabolic risk: The logic for intervention

Mark A Pereira, Thomas E Kottke, Courtney Jordan, Patrick J. O'Connor, Nicolaas P. Pronk, Rita Carreón

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations


Cardiometabolic risk (CMR), also known as metabolic syndrome or insulin resistance syndrome, comprises obesity (particularly central or abdominal obesity), high triglycerides, low HDL, elevated blood pressure, and elevated plasma glucose. Leading to death from diabetes, heart disease, and stroke, the root cause of CMR is inadequate physical activity, a Western diet identified primarily by low intake of fruits, vegetables, and whole grains, and high in saturated fat, as well as a number of yet-to-be-identified genetic factors. While the pathophysiological pathways related to CMR are complex, the universal need for adequate physical activity and a diet that emphasizes fruits and vegetables and whole grains, while minimizing food high in added sugars and saturated fat suggests that these behaviors are the appropriate focus of intervention.

Original languageEnglish (US)
Pages (from-to)2568-2584
Number of pages17
JournalInternational journal of environmental research and public health
Issue number10
StatePublished - Oct 2009


  • Cardiometabolic risk
  • Diet
  • Physical activity
  • Prevention
  • Strategy
  • Treatment


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