Presumed primary immune-mediated thrombocytopenia in four cats

Domenico Bianco, P. Jane Armstrong, Robert J Washabau, VMD, PhD

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Feline primary immune-mediated thrombocytopenia (pIMT) is a rare hematological disorder. Platelet-bound antibody assays for cats have variable specificity and sensitivity and are not widely available. Diagnosis of pIMT is made on the basis of exclusion of other identifiable causes of thrombocytopenia and the response to immunosuppressive therapy. This report describes four cats with severe thrombocytopenia and no detectable underlying disease. One cat was euthanased because of pulmonary hemorrhage, while the other cats had frequent relapses, two of these cats developed diabetes mellitus due to long-term corticosteroid therapy. In these cats IMT had a chronic course and responded poorly to therapy with prednisolone. Alternative immunomodulatory drugs may be considered in the treatment of feline IMT.

Original languageEnglish (US)
Pages (from-to)495-500
Number of pages6
JournalJournal of Feline Medicine and Surgery
Volume10
Issue number5
DOIs
StatePublished - Oct 2008

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