Preservation of stem cells

Jacob Hanna, Allison Hubel

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations

Abstract

Adult stem cells (hematopoietic and mesenchymal) have demonstrated tremendous human therapeutic potential. Currently, human embryonic stem cells are used principally for understanding development and disease progression but also hold tremendous therapeutic potential. The ability to preserve stem cells is critical for their use in clinical and research applications. Preservation of cells permits the transportation of cells between sites, as well as completion of safety and quality control testing. Preservation also permits the development of a 'manufacturing paradigm' for cell therapies, thereby maximizing the number of products that can be produced at a given facility. In this article, we will review modes of preservation and the current status of preservation of hematopoietic, mesenchymal and human embryonic stem cells. Current and emerging issues in the area of stem cell preservation will also be described.

Original languageEnglish (US)
Pages (from-to)134-137
Number of pages4
JournalOrganogenesis
Volume5
Issue number3
DOIs
StatePublished - 2009

Keywords

  • Cell therapy
  • Cryopreservation
  • Preservation
  • Stabilization
  • Stem cells

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