Preservation of Biospecimens at Ambient Temperature: Special Focus on Nucleic Acids and Opportunities for the Biobanking Community

Rolf Muller, Fay Betsou, Michael G. Barnes, Keith Harding, Jacques Bonnet, Olga Kofanova, John H. Crowe, Erica Benson, Alexandre Bulla, Rodrigo Chuaqui, Judith Ann Clements, Domenico Coppola, Yvonne De Souza, Annemieke De Wilde, James Eliason, Barbara Glazer, William Grizzle, Elaine Gunter, Verity Hodgkinson, Allison HubelTheresa Kokkat, Iren Koppandi, Jacqueline Mackenzie-Dodds, Rebecca Pugh, Vinagolu Rajasekhar, Katheryn Shea, Amy Skubitz, Mark Sobel, Stella Somiari, Gunnel Tybring, Klara Valyi-Nagy

Research output: Contribution to journalArticle

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Abstract

Several approaches to the preservation of biological materials at ambient temperature and the relative impact on sample stability and degradation are reviewed, with a focus on nucleic acids. This appraisal is undertaken within the framework of biobank risk, quality management systems, and accreditation, with a view to assessing how best to apply ambient temperature sample storage to ensure stability, reduce costs, improve handling logistics, and increase the efficiency of biobank procedures.

Original languageEnglish (US)
Pages (from-to)89-98
Number of pages10
JournalBiopreservation and Biobanking
Volume14
Issue number2
DOIs
StatePublished - Apr 1 2016

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Muller, R., Betsou, F., Barnes, M. G., Harding, K., Bonnet, J., Kofanova, O., Crowe, J. H., Benson, E., Bulla, A., Chuaqui, R., Clements, J. A., Coppola, D., De Souza, Y., De Wilde, A., Eliason, J., Glazer, B., Grizzle, W., Gunter, E., Hodgkinson, V., ... Valyi-Nagy, K. (2016). Preservation of Biospecimens at Ambient Temperature: Special Focus on Nucleic Acids and Opportunities for the Biobanking Community. Biopreservation and Biobanking, 14(2), 89-98. https://doi.org/10.1089/bio.2015.0022