Prescription Medication Use Among Community-Based U.S. Adults With Chronic Low Back Pain: A Cross-Sectional Population Based Study

Anna Shmagel, Linh Ngo, Kristine Ensrud, Robert Foley

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Many classes of medications have been evaluated in chronic low back pain (cLBP), however their utilization in the community remains unclear. We examined patterns of prescription medication use among Americans with cLBP in a nationally representative, community-based sample. The Back Pain Survey was administered to a representative sample of U.S. adults aged 20 to 69 years (N = 5,103) during the 2009 to 2010 cycle of the National Health and Nutrition Examination Survey. cLBP was defined as self-reported pain in the area between the lower posterior margin of the ribcage and the horizontal gluteal fold on most days for at least 3 months (N = 700). Home-based interviews with pill bottle verification were used to capture commonly prescribed medications for chronic pain. Among the sample of U.S. adults with cLBP aged 20 to 69 years, 36.9% took at least 1 prescription pain medication in the past 30 days; of them, 18.8% used opioids, 9.7% nonsteroidal anti-inflammatory drugs, 8.5% muscle relaxants, and 6.9% gabapentin or pregabalin. Nonpain antidepressants and hypnotics were used by 17.8% and 4.7%, respectively. Opioids were used long-term in 76.9% of cases (median = 2 years) and were frequently coadministered with antidepressants, benzodiazepines, or hypnotics. Ninety-four percent of prescription opioids in the cLBP population were used by individuals with less than a college education. Opioids were the most widely used prescription analgesic class in community-based U.S. adults with cLBP and were often coadministered with other central nervous system-active medications. Opioid use was highly prevalent among less educated Americans with cLBP. Perspective: Because prescription opioid use is an issue of national concern, we examined pain-related prescription medication use in community-dwelling U.S. adults with cLBP. Opioids were the most common prescription pain medication, typically used long-term, in combination with other central nervous system-active agents, and disproportionately among individuals with less than a college education.

Original languageEnglish (US)
Pages (from-to)1104-1112
Number of pages9
JournalJournal of Pain
Volume19
Issue number10
DOIs
StatePublished - Oct 2018

Fingerprint

Low Back Pain
Prescriptions
Opioid Analgesics
Population
Pain
Hypnotics and Sedatives
Antidepressive Agents
Central Nervous System Agents
Independent Living
Education
Nutrition Surveys
Back Pain
Benzodiazepines
Chronic Pain
Analgesics
Anti-Inflammatory Agents
Central Nervous System
Interviews
Muscles
Pharmaceutical Preparations

Keywords

  • Low back pain
  • analgesics
  • epidemiology
  • opioids

Cite this

Prescription Medication Use Among Community-Based U.S. Adults With Chronic Low Back Pain : A Cross-Sectional Population Based Study. / Shmagel, Anna; Ngo, Linh; Ensrud, Kristine; Foley, Robert.

In: Journal of Pain, Vol. 19, No. 10, 10.2018, p. 1104-1112.

Research output: Contribution to journalArticle

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