PRES secondary to autonomic dysreflexia: A case series and review of the literature

Molly E. Hubbard, Aaron A. Phillips, Rebecca Charbonneau, Jordan W. Squair, Ann M. Parr, Andrei Krassioukov

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Context: Autonomic dysreflexia (AD) is a complex syndrome seen in patients with spinal cord injuries (SCI) and can be life-threatening with a significant negative impact on the health of the individual. Posterior reversible encephalopathy syndrome (PRES) is thought to be caused, in part, by rapid elevations in blood pressure; leading to posterior cerebral circulatory edema. This can result in seizures, blindness and can progress to fatal intracranial hemorrhages. Findings: Here we present two cases of patients with SCI who developed PRES from AD. Each patient was correctly diagnosed, leading to appropriate treatment of the factors leading to their AD and subsequent resolution of their PRES symptoms. Conclusions/Clinical Relevance: In SCI patients who present with new seizures, visual deficits, or other neurologic signs, PRES should be considered as a part of the differential diagnosis as a good outcome relies on rapid recognition and treatment of AD.

Original languageEnglish (US)
Pages (from-to)606-612
Number of pages7
JournalJournal of Spinal Cord Medicine
Issue number4
Early online dateMay 29 2019
StatePublished - May 29 2019

Bibliographical note

Publisher Copyright:
© The Academy of Spinal Cord Injury Professionals, Inc. 2019.


  • Autonomic dysreflexia
  • Posterior reversible encephalopathy syndrome
  • Spinal cord injury


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