Preparation, stability, and in vitro performance of vesicles made with diblock copolymers

Dennis Discher, James Lee, Harry Bermudez, Daniel Hammer, Frank Bates

Research output: Contribution to journalConference article

Abstract

Vesicles made completely from diblock copolymers-polymersomes-can be stably prepared by a wide range of techniques common to liposomes. Processes such as film rehydration, sonication, and extrusion can generate many-micron giants as well as monodisperse, 100 nm vesicles of PEO-PEE (polyethylenoxide - polyethylethylene) or PEO-PBD (polyethylenoxide - polybutadiene). Results are presented that potentiate a broad new class of technologically useful, polymerbased vesicles.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

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