Preparation of optically pure alkyl 3-(hetero-2-yl)-3-hydroxypropanoates by Candida parapsilosis ATCC 7330 mediated deracemisation

D. Titu, Anju Chadha

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Deracemisation of racemic alkyl 3-(hetero-2-yl)-3-hydroxypropanoates using whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the 'S' enantiomer in high enantiomeric excess (up to >99% ee) and isolated yields (up to 75%).

Original languageEnglish (US)
Pages (from-to)168-172
Number of pages5
JournalJournal of Molecular Catalysis B: Enzymatic
Volume52-53
Issue number1-4
DOIs
StatePublished - Jun 2008

Bibliographical note

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

Keywords

  • Alkyl 3-(hetero-2-yl)-3-hydroxypropanoates
  • Candida parapsilosis ATCC 7330
  • Deracemisation
  • Hetero-2-yl
  • β-Hydroxy ester

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