Preparation of optically pure alkyl 3-(hetero-2-yl)-3-hydroxypropanoates by Candida parapsilosis ATCC 7330 mediated deracemisation

D. Titu; Anju Chadha

doi:10.1016/j.molcatb.2007.11.006

Preparation of optically pure alkyl 3-(hetero-2-yl)-3-hydroxypropanoates by Candida parapsilosis ATCC 7330 mediated deracemisation

D. Titu, Anju Chadha

Chemical Engineering and Materials Science

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Deracemisation of racemic alkyl 3-(hetero-2-yl)-3-hydroxypropanoates using whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the 'S' enantiomer in high enantiomeric excess (up to >99% ee) and isolated yields (up to 75%).

Original language	English (US)
Pages (from-to)	168-172
Number of pages	5
Journal	Journal of Molecular Catalysis B: Enzymatic
Volume	52-53
Issue number	1-4
DOIs	https://doi.org/10.1016/j.molcatb.2007.11.006
State	Published - Jun 2008

Keywords

Alkyl 3-(hetero-2-yl)-3-hydroxypropanoates
Candida parapsilosis ATCC 7330
Deracemisation
Hetero-2-yl
β-Hydroxy ester

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10.1016/j.molcatb.2007.11.006

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title = "Preparation of optically pure alkyl 3-(hetero-2-yl)-3-hydroxypropanoates by Candida parapsilosis ATCC 7330 mediated deracemisation",

abstract = "Deracemisation of racemic alkyl 3-(hetero-2-yl)-3-hydroxypropanoates using whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the 'S' enantiomer in high enantiomeric excess (up to >99% ee) and isolated yields (up to 75%).",

keywords = "Alkyl 3-(hetero-2-yl)-3-hydroxypropanoates, Candida parapsilosis ATCC 7330, Deracemisation, Hetero-2-yl, β-Hydroxy ester",

author = "D. Titu and Anju Chadha",

year = "2008",

month = jun,

doi = "10.1016/j.molcatb.2007.11.006",

language = "English (US)",

volume = "52-53",

pages = "168--172",

journal = "Journal of Molecular Catalysis B: Enzymatic",

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T1 - Preparation of optically pure alkyl 3-(hetero-2-yl)-3-hydroxypropanoates by Candida parapsilosis ATCC 7330 mediated deracemisation

AU - Titu, D.

AU - Chadha, Anju

PY - 2008/6

Y1 - 2008/6

N2 - Deracemisation of racemic alkyl 3-(hetero-2-yl)-3-hydroxypropanoates using whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the 'S' enantiomer in high enantiomeric excess (up to >99% ee) and isolated yields (up to 75%).

AB - Deracemisation of racemic alkyl 3-(hetero-2-yl)-3-hydroxypropanoates using whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the 'S' enantiomer in high enantiomeric excess (up to >99% ee) and isolated yields (up to 75%).

KW - Alkyl 3-(hetero-2-yl)-3-hydroxypropanoates

KW - Candida parapsilosis ATCC 7330

KW - Deracemisation

KW - Hetero-2-yl

KW - β-Hydroxy ester

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DO - 10.1016/j.molcatb.2007.11.006

M3 - Article

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VL - 52-53

SP - 168

EP - 172

JO - Journal of Molecular Catalysis B: Enzymatic

JF - Journal of Molecular Catalysis B: Enzymatic

IS - 1-4

ER -

Preparation of optically pure alkyl 3-(hetero-2-yl)-3-hydroxypropanoates by Candida parapsilosis ATCC 7330 mediated deracemisation

Abstract

Keywords

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