Preparation of dopamine-modified boron nanoparticles

Zhe Gao; Nathan I. Walton; Alexander Malugin; Hamidreza Ghandehari; Ilya Zharov

doi:10.1039/c1jm12655e

Preparation of dopamine-modified boron nanoparticles

Zhe Gao, Nathan I. Walton, Alexander Malugin, Hamidreza Ghandehari, Ilya Zharov

Mechanical Engineering

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

We developed a method to obtain water-dispersible boron nanoparticles (BNPs) as a potential boron delivery agent for cancer treatment. The 40 nm nanoparticles are prepared by mechanical milling in undecylenic acid followed by ligand exchange with dopamine. These particles can be rendered fluorescent by the attachment of a fluorophore to the primary amine of the dopamine, which could be used to locate the particles in a cell media. Dopamine-modified boron nanoparticles did not show signs of toxicity toward murine macrophage cells.

Original language	English (US)
Pages (from-to)	877-882
Number of pages	6
Journal	Journal of Materials Chemistry
Volume	22
Issue number	3
DOIs	https://doi.org/10.1039/c1jm12655e
State	Published - Jan 21 2012

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AU - Ghandehari, Hamidreza

AU - Zharov, Ilya

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Preparation of dopamine-modified boron nanoparticles

Abstract

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