Prenatal epidemiology of pediatric tumors.

J. A. Ross, A. R. Swensen

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

With the exception of a small percentage of cases attributable to hereditary cancer syndromes (eg, familial retinoblastoma) or genetic syndromes (Down syndrome), the etiology of most childhood cancers is unknown. Recent epidemiologic studies have focused on the prenatal period and have investigated potential associations with parental age, cigarette smoking, birth weight of the child, parental occupational exposures, and specific environmental exposures. The following challenges lie ahead for future epidemiologic studies of childhood cancer: 1) improvement of diagnostic classification; 2) improved methods for exposure assessment; 3) evaluation of data from molecular biology to generate biologically derived hypotheses; and 4) incorporation of markers of genetic susceptibility when feasible.

Original languageEnglish (US)
Pages (from-to)234-241
Number of pages8
JournalCurrent oncology reports
Volume2
Issue number3
DOIs
StatePublished - May 2000

Fingerprint Dive into the research topics of 'Prenatal epidemiology of pediatric tumors.'. Together they form a unique fingerprint.

  • Cite this