Preliminary observations with a technique for measuring current spread in the rat brain

M. Potegal, A. Blau, S. Miller

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Intracranial spread of current from monopolar and bipolar electrode configurations was evaluated by using a motor effect of VII nerve stimulation. A tripolar electrode was lowered through the medulla toward the nerve in 1 mm steps; the currents necessary to produce threshold levels of sustained vibrissae vibration with monopolar and bipolar combinations of tips were determined at each step. Bipolar stimulation had a steep gradient and its effects were largely confined to a region within 2 mm of the minimum threshold point. Monopolar stimulation had a broader gradient and spread further. This technique appears promising for quantitative evaluation of ICS characteristics.

Original languageEnglish (US)
Pages (from-to)769-773
Number of pages5
JournalPhysiology and Behavior
Volume25
Issue number5
DOIs
StatePublished - Jan 1 1980

Keywords

  • Brain stimulation
  • Current spread
  • Monopolar vs bipolar
  • VII nerve
  • Vibrissae movement

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