Pregnancy in perinatally HIV-infected adolescents

Background: Long-term survival of patients with congenital human immunodeficiency virus (HIV) infection has resulted in a growing cohort of perinatally infected adolescents and young adults who are sexually active and becoming pregnant. Cases: Two cases are presented to report our management of pregnancies resulting from unprotected sexual practices in perinatally HIV-infected adolescents who were HIV serodiscordant. An integrated approach, involving the specialties of pediatrics, obstetrics and gynecology, and infectious disease, along with social services, was used to provide comprehensive care to these patients. Conclusion: There is a need to address reproductive health issues, especially risky sexual behaviors, in adolescents who are HIV infected.