Preferential utilization of d-Lactate by Shewanella oneidensis

Evan D. Brutinel, Jeffrey A. Gralnick

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Shewanella oneidensis couples oxidation of lactate to respiration of many substrates. Here we report that llpR (L-lactate-positive regulator, SO_3460) encodes a positive regulator of L-lactate utilization distinct from previously studied regulators. We also demonstrate D-lactate inhibition of L-lactate utilization in S. oneidensis, resulting in preferential utilization of the D isomer.

Original languageEnglish (US)
Pages (from-to)8474-8476
Number of pages3
JournalApplied and environmental microbiology
Issue number23
StatePublished - 2012


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