Predominance of bla CTX-M-65 and bla CTX-M-55 in extended-spectrum β-lactamase-producing Escherichia coli from raw retail chicken in South Korea

Hyeeun Park, Jinshil Kim, Sangryeol Ryu, Byeonghwa Jeon

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Objectives: Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) are a serious public health concern worldwide. The aim of this study was to characterise ESBL-EC isolated from raw retail chicken in South Korea. Methods: The antimicrobial resistance, phylogenetic group and virulence gene prevalence of 67 ESBL-EC isolated from retail chicken in South Korea were investigated. Results: All of the isolates possessed bla CTX-M genes, predominantly bla CTX-M-65 (52.2%) and bla CTX-M-55 (25.4%), and three isolates harboured both bla CTX-M-65 and bla CTX-M-55 . More than one-half of the ESBL-EC strains also carried bla TEM . Antimicrobial susceptibility testing revealed that 98.5% of the strains were multidrug-resistant (MDR). Phylogenetic analysis showed that group A was predominant (56.7%), followed by B1 (19.4%), E (8.9%), B2 (6.0%) and D (6.0%). Virulence genes associated with extraintestinal pathogenic E. coli (ExPEC) were frequently detected in isolates of phylogenetic groups B1, B2, D and E. Conclusion: The results in this study demonstrate that retail chicken in South Korea is highly contaminated with MDR ESBL-EC and may serve as a reservoir for transmitting ExPEC to humans.

Original languageEnglish (US)
Pages (from-to)216-220
Number of pages5
JournalJournal of Global Antimicrobial Resistance
Volume17
DOIs
StatePublished - Jun 2019
Externally publishedYes

Bibliographical note

Funding Information:
This research was supported by a grant [ 16162MFDS029 ] from the Ministry of Food and Drug Safety, South Korea . HP and JK were supported by the BK21 Plus Program of the Department of Agricultural Biotechnology, Seoul National University, Seoul, South Korea.

Keywords

  • Antimicrobial resistance
  • CTX-M
  • Chicken
  • ESBL
  • Escherichia coli
  • Extended-spectrum β-lactamase

Fingerprint Dive into the research topics of 'Predominance of bla <sub>CTX-M-65</sub> and bla <sub>CTX-M-55</sub> in extended-spectrum β-lactamase-producing Escherichia coli from raw retail chicken in South Korea'. Together they form a unique fingerprint.

Cite this