Predictors of need for catheterisation and urinary retention after radical cystectomy and orthotopic neobladder in male patients

Saum Ghodoussipour, Seyedeh Sanam Ladi Seyedian, Daniel Jiang, Jacob Lifton, Hamed Ahmadi, Kevin Wayne, Gus Miranda, Jie Cai, Hooman Djaladat, Anne Schuckman, Sumeet Bhanvadia, Siamak Daneshmand

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: To investigate the prevalence of catheterisation and urinary retention in male patients with bladder cancer after radical cystectomy (RC) and orthotopic neobladder (ONB) and to identify potential predictors. Patients and Methods: Using an Institutional Review Board approved, prospectively maintained bladder cancer database, we collected information using a diversion-related questionnaire from 299 consecutive male patients with bladder cancer upon postoperative clinic visit. Urinary retention was defined as ≥3 catheterisations/day or a self-reported inability to void without a catheter. Uni- and multivariable Cox regression analysis was performed to identify predictors of catheterisation and urinary retention. Results: Self-catheterisation was reported in 51 patients (17%), of whom, 22 (7.4% of the total patients) were in retention. Freedom from any catheterisation at 3, 5, and 10 years after RC was 85%, 77%, and 62%, respectively. Freedom from retention at 3, 5, and 10 years after RC was 93%, 88%, and 79%, respectively. Multivariable Cox regression showed that higher body mass index (BMI; ≥27 kg/m2) significantly increased the need for catheterisation (hazard ratio [HR] 2.34, 95% confidence interval [CI] 1.26–4.32) as well as retention (HR 5.20, 95% CI 1.74–15.51). Greater medical comorbidity (Charlson Comorbidity Index score ≥2) correlated with the need for any catheterisation (HR 1.84, 95% CI 1.02–3.3), but not retention. Pathological stage and type of diversion were not significant predictors of the need to catheterise or urinary retention. Conclusion: In males undergoing RC with ONB, retention requiring catheterisation to void is uncommon. Patients with a BMI of ≥27 kg/m2 are at significantly increased risk of retention and need for self-catheterisation.

Original languageEnglish (US)
Pages (from-to)304-310
Number of pages7
JournalBJU International
Volume128
Issue number3
DOIs
StatePublished - Sep 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2020 The Authors BJU International © 2020 BJU International Published by John Wiley & Sons Ltd

Keywords

  • #BladderCancer
  • #blcsm
  • bladder cancer
  • cystectomy
  • orthotopic neobladder
  • retention
  • urinary diversion

PubMed: MeSH publication types

  • Journal Article

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