Predictors and moderators of treatment outcome in a randomized clinical trial for binge-eating disorder

Lisa M. Anderson, Kathryn M. Smith, Lauren M. Schaefer, Ross D. Crosby, Li Cao, Scott G. Engel, Scott J. Crow, Stephen A. Wonderlich, Carol B. Peterson

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

OBJECTIVE: The current study examined predictors and moderators of two interventions for binge-eating disorder (BED).

METHOD: Participants were 112 adults with BED ( M age = 39.7 ± 13.4 years; M BMI = 35.1 ± 13.4 kg/m²; 82% female; 91% Caucasian) randomly assigned to integrative cognitive-affective therapy for BED (ICAT-BED) or guided self-help cognitive-behavioral therapy (CBTgsh). Generalized linear models examined predictors and moderators of objective binge-eating episode (OBE) frequency and OBE abstinence at end-of-treatment (EOT) and 6-month follow-up (FU).

RESULTS: Lower levels of baseline dietary restraint and emotion regulation difficulties predicted greater reductions in OBE frequency at EOT and FU, respectively. At EOT, greater pretreatment self-control predicted greater reductions in OBE frequency in ICAT-BED than CBTgsh ( ps < .05). In addition, low shape/weight overvaluation predicted greater reductions in OBE frequency in ICAT-BED than CBTgsh, whereas high shape/weight overvaluation predicted comparable reductions in OBE frequency across treatments at EOT ( ps < .02). At EOT and FU, greater baseline actual-ideal self-discrepancy predicted significantly greater reductions in OBE frequency in ICAT-BED, than CBTgsh ( ps < .02). No significant predictor or moderator effects were observed for models examining OBE abstinence.

CONCLUSION: This study identified two general predictors and four moderators of BED treatment response. However, only one predictor (actual-ideal self-discrepancy) interacted with treatment type to differentially predict OBE frequencies at both EOT and FU. Altogether, findings suggest that ICAT-BED may confer specific and durable improvements in OBE frequencies among individuals with high actual-ideal self-discrepancy. Therefore, patients demonstrating these characteristics may be more likely to benefit from ICAT-BED. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Original languageEnglish (US)
Pages (from-to)631-642
Number of pages12
JournalJournal of consulting and clinical psychology
Volume88
Issue number7
DOIs
StatePublished - Jul 2020

Bibliographical note

Funding Information:
Research reported in this article was supported by the National Institute of Mental Health of the National Institutes of Health under Awards R34 MH099040-01A1, R34 MH098995-01A1, and T32 MH082761. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Publisher Copyright:
© 2020 American Psychological Association.

Keywords

  • Binge-eating disorder
  • Moderators
  • Predictors
  • Psychotherapy
  • Treatment outcome
  • Humans
  • Middle Aged
  • Male
  • Treatment Outcome
  • Cognitive Behavioral Therapy
  • Binge-Eating Disorder/psychology
  • Adult
  • Female

PubMed: MeSH publication types

  • Randomized Controlled Trial
  • Journal Article

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