Predicting grade of prostate cancer using image analysis software

V. Guru Anand, G. Hari Krishna, G. Mohandass, R. J. Hemalatha, Sandhya Sundaram

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

The prognosis of prostate cancer is determined by using the Gleason grading system. This grading is done based upon the tissue pattern obtained from the tumor, after staining the biopsy with Heamatoxylin and Eosin (H&E). Presently, experienced pathologists manually grade on prostate cancers subjectively. The grading therefore depends upon the experience of the pathologists, quality of the staining and various other factors. To overcome this, an image analysis system is developed using MATLAB that can examine the biopsy image and grade it objectively. Size distribution of the sample image is utilized to recognize the pattern. The prediction is done based on the pattern of lumen, nuclei and the glandular organization in the representative areas of biopsy-image taken from a microscope. The results obtained show a remarkable accuracy and is closer to the manual grading scores. This Computer-Adaptive- Diagnosis (CAD) system may be used as a powerful adjunct for effectively diagnosing the prostate cancers and grading them.

Original languageEnglish (US)
Title of host publicationProceedings of the 2nd International Conference on Trendz in Information Sciences and Computing, TISC-2010
Pages122-124
Number of pages3
DOIs
StatePublished - Dec 1 2010
Event2nd International Conference on Trendz in Information Sciences and Computing, TISC-2010 - Chennai, India
Duration: Dec 17 2010Dec 19 2010

Publication series

NameProceedings of the 2nd International Conference on Trendz in Information Sciences and Computing, TISC-2010

Other

Other2nd International Conference on Trendz in Information Sciences and Computing, TISC-2010
CountryIndia
CityChennai
Period12/17/1012/19/10

Keywords

  • Gleason grading
  • Heamatoxylin and Eosin (H&E)
  • Pattern recognition
  • Prostate cancer

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  • Cite this

    Guru Anand, V., Hari Krishna, G., Mohandass, G., Hemalatha, R. J., & Sundaram, S. (2010). Predicting grade of prostate cancer using image analysis software. In Proceedings of the 2nd International Conference on Trendz in Information Sciences and Computing, TISC-2010 (pp. 122-124). [5714621] (Proceedings of the 2nd International Conference on Trendz in Information Sciences and Computing, TISC-2010). https://doi.org/10.1109/TISC.2010.5714621