Pre-operative cellularity mapping and intra-MRI surgery

Potential for improving neurosurgical biopsies

Clark C. Chen, Nathan S. White, Nikdokht Farid, Peter Kobalka, Lawrence Hansen, Matthew Pearn, Anders M. Dale

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Stereotactic biopsies are frequently performed to secure definitive diagnosis for brain tumor patients. Fundamentally, there are two major difficulties in these endeavors. First, because of intra-tumoral heterogeneity inherent in many forms of brain cancer, biopsies taken from one region may yield a different diagnosis than if another area is biopsied. Second, stereotactic needle biopsies inherently rely on mathematical algorithms for targeting, without real-time visualization of the actual biopsy site. This article describes the novel MRI-based technologies that can potentially afford neurosurgeons the opportunity to address these challenges.

Original languageEnglish (US)
Pages (from-to)1-5
Number of pages5
JournalExpert Review of Medical Devices
Volume12
Issue number1
DOIs
StatePublished - Jan 1 2014

Fingerprint

Biopsy
Magnetic resonance imaging
Surgery
Brain Neoplasms
Brain
Needle Biopsy
Needles
Technology
Tumors
Visualization

Keywords

  • MRI-guided surgery
  • brain tumor
  • glioblastoma multiforme
  • restriction spectrum imaging
  • stereotactic biopsy

Cite this

Pre-operative cellularity mapping and intra-MRI surgery : Potential for improving neurosurgical biopsies. / Chen, Clark C.; White, Nathan S.; Farid, Nikdokht; Kobalka, Peter; Hansen, Lawrence; Pearn, Matthew; Dale, Anders M.

In: Expert Review of Medical Devices, Vol. 12, No. 1, 01.01.2014, p. 1-5.

Research output: Contribution to journalReview article

Chen, Clark C. ; White, Nathan S. ; Farid, Nikdokht ; Kobalka, Peter ; Hansen, Lawrence ; Pearn, Matthew ; Dale, Anders M. / Pre-operative cellularity mapping and intra-MRI surgery : Potential for improving neurosurgical biopsies. In: Expert Review of Medical Devices. 2014 ; Vol. 12, No. 1. pp. 1-5.
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