Abstract
Purpose/Objectives: There is little consensus regarding the application of stereotactic radiotherapy (SRT) in pediatrics. We evaluated patterns of pediatric SRT practice through an international research consortium. Materials and Methods: Eight international institutions with pediatric expertise completed a 124-item survey evaluating patterns of SRT use for patients 21 years old and younger. Frequencies of SRT use and median margins applied with and without SRT were evaluated. Results: Across institutions, 75% reported utilizing SRT in pediatrics. SRT was used in 22% of brain, 18% of spine, 16% of other bone, 16% of head and neck, and <1% of abdomen/pelvis, lung, and liver cases across sites. Of the hypofractionated SRT cases, 42% were delivered with definitive intent. Median gross tumor volume to planning target volume margins for SRT versus non-SRT plans were 0.2 versus 1.4 cm for brain, 0.3 versus 1.5 cm for spine/other bone, 0.3 versus 2.0 cm for abdomen/pelvis, 0.7 versus 1.5 cm for head and neck, 0.5 versus 1.7 cm for lung, and 0.5 versus 2.0 cm for liver sites. Conclusions: SRT is commonly utilized in pediatrics across a range of treatment sites. Margins used for SRT were substantially smaller than for non-SRT planning, highlighting the utility of this approach in reducing treatment volumes. ©
Original language | English (US) |
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Pages (from-to) | 522-526 |
Number of pages | 5 |
Journal | Journal of pediatric hematology/oncology |
Volume | 40 |
Issue number | 7 |
DOIs | |
State | Published - Oct 1 2018 |
Bibliographical note
Funding Information:Supported in part by a research grant from Elekta, AB. However, the data and its interpretation is the property of the contributing authors and participating institutions.
Publisher Copyright:
Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.
Keywords
- pediatric stereotactic radiosurgery
- stereotactic body radiation therapy
- stereotactic radiosurgery
PubMed: MeSH publication types
- Journal Article
- Multicenter Study