Potential roles for transposable elements in creating imprinted expression

Sarah N Anderson, Nathan M Springer

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Changes in gene expression can have profound effects on phenotype. Nature has provided many complex patterns of gene regulation such as imprinting. Imprinted genes exhibit differences in the expression of the maternal and paternal alleles, even though they reside in the same nucleus with access to the same trans-acting factors. Significant attention has been focused on the potential reasons that imprinted expression could be beneficial and stabilized by selection. However, less attention has focused on understanding how imprinted expression might arise or decay. We discuss the evidence for frequent turnover of imprinted expression based on evolutionary analyses in plants and the potential role for transposable elements (TEs) in creating imprinted expression patterns.

Original languageEnglish (US)
Pages (from-to)8-14
Number of pages7
JournalCurrent Opinion in Genetics and Development
Volume49
DOIs
StatePublished - Apr 1 2018

Fingerprint

DNA Transposable Elements
Trans-Activators
Genes
Alleles
Mothers
Phenotype
Gene Expression

PubMed: MeSH publication types

  • Journal Article
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

Cite this

Potential roles for transposable elements in creating imprinted expression. / Anderson, Sarah N; Springer, Nathan M.

In: Current Opinion in Genetics and Development, Vol. 49, 01.04.2018, p. 8-14.

Research output: Contribution to journalReview article

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