Posterior amorphous corneal dystrophy

Emmett F. Carpel, Robert J. Sigelman, Donald J. Doughman

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


A family of ten individuals aged 18 months to 75 years had biomicroscopic findings consisting of large, amorphous, sheet-like opacifications of the posterior stroma and Descemet's membrane, and alterations of the endothelium. A uniform thinning of the cornea was present. These findings do not conform to previously described corneal dystrophies. The condition appears minimally progressive and the three-generation pedigree indicated an autosomal-dominant inheritance pattern.

Original languageEnglish (US)
Pages (from-to)629-632
Number of pages4
JournalAmerican journal of ophthalmology
Issue number5
StatePublished - May 1977


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