Porous polymer scaffold for on-site delivery of stem cells - Protects from oxidative stress and potentiates wound tissue repair

Keyphrases

• Oxidative Stress 100%
• Tissue Repair 100%
• Stem Cells 100%
• Wound Tissue 100%
• Porous Polymer Scaffold 100%
• Polyethylene Glycol 66%
• Bone Marrow Cells 66%
• Gene Expression 33%
• Clinical Evaluation 33%
• Inflammatory Cytokines 33%
• Interleukin-8 33%
• Interleukin-10 33%
• Transplantation 33%
• Wound Healing 33%
• Protective Effect 33%
• Fibroblast Proliferation 33%
• Engraftment 33%
• Polyurethane 33%
• Vascular Function 33%
• Polymer Matrix 33%
• Network Approach 33%
• Cell Transplantation 33%
• Porosity 33%
• Cytocompatible 33%
• Interleukin-1β 33%
• Physicochemical Properties 33%
• Matrix metalloproteinase-2 (MMP-2) 33%
• Immunostaining 33%
• Matrix Metalloproteinase 13 (MMP13) 33%
• Acidic pH 33%
• Early Healing 33%
• Healing Period 33%
• Catalase Activity 33%
• Splint 33%
• Interleukin-13 (IL-13) 33%
• Collagen Deposition 33%
• Decreased Expression 33%
• Antioxidant Enzyme Activity 33%
• Polymer Network 33%
• Anti-inflammatory Cytokines 33%
• Injury Levels 33%
• Semi-IPN 33%
• Mouse Bone Marrow 33%
• Cell Delivery 33%
• Transplant Experiment 33%
• Excisional 33%
• H2O2-induced Apoptosis 33%
• Porous Polymer Networks 33%
• Tissue Closure 33%
• Polyurethane Scaffold 33%
• Fold Increase 33%
• Cell Delivery System 33%
• Cellular Penetration 33%

Engineering

• Stem Cell 100%
• Porosity 100%
• Network Polymer 75%
• Bone Marrow Stem Cell 50%
• Inflammatory Cytokine 50%
• Proof-of-Concept 25%
• Polyurethan 25%
• Delivery Vehicle 25%
• Enzymatic Activity 25%
• Fold Increase 25%
• Polymeric Matrix 25%
• Fibroblast Proliferation 25%
• Injury Site 25%
• Polyurethane Scaffold 25%

Material Science

• Polymer Network 100%
• Stem Cell 100%
• Polyurethane 66%
• Chemical Property 33%
• Hydrogen Peroxide 33%
• Gene Expression 33%
• Antioxidant 33%
• Catalase 33%
• Fibroblast 33%
• Enzyme Activity 33%