Porcine circovirus 3 in North and South America: Epidemiology and genetic diversity

Viviane Sisdelli Assao, Marcus Rebouças Santos, Carlos Eduardo Real Pereira, Fabio Vannucci, Abelardo Silva-Júnior

Research output: Contribution to journalArticlepeer-review


Porcine circovirus 3 (PCV3) is a recently discovered virus that has been detected in the swine population worldwide. PCV3 infection has been associated with several signs, but its pathogenicity is currently uncertain. This review article aimed to analyse the PCV3 strains that circulate in different countries in North and South America. We demonstrated the main regions of polymorphisms in the capsid protein structure. Furthermore, we found that PCV3 has at least six different lineages circulating in the Americas. Additional studies are required to determine the role of PCV3 in different clinical syndromes and its epidemiology in swine herds in North and South American countries.

Original languageEnglish (US)
Pages (from-to)2949-2956
Number of pages8
JournalTransboundary and Emerging Diseases
Issue number6
Early online dateJul 26 2021
StatePublished - Nov 2021

Bibliographical note

Funding Information:
This work was supported by CNPq, FAPEMIG and CAPES.

Publisher Copyright:
© 2021 Wiley-VCH GmbH


  • epidemiology
  • molecular evolution
  • porcine circovirus 3
  • swine


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