Polymorphous Adenocarcinoma, Low Grade Variant, Colliding with a Neurofibroma

Nikolaos G. Katsoulas; Konstantinos I. Tosios; Hannah Afwerke Lynch; Rachel Uppgaard; Ioannis G. Koutlas

doi:10.1007/s12105-021-01377-7

Polymorphous Adenocarcinoma, Low Grade Variant, Colliding with a Neurofibroma

Nikolaos G. Katsoulas, Konstantinos I. Tosios, Hannah Afwerke Lynch, Rachel Uppgaard, Ioannis G. Koutlas

Research output: Contribution to journal › Article › peer-review

Abstract

Collision tumors, composed of two distinct benign or malignant neoplasms, are rarely reported in the oral cavity. We present a case of a 61-year-old female with an asymptomatic non-demarcated lump on the soft palate of unknown duration. An incisional biopsy revealed the presence of two neoplastic populations, a neurofibroma that was partially infiltrated by a polymorphous adenocarcinoma, low-grade variant. Total surgical excision was performed, with uneventful follow-up period. The development of collision tumors may be incidental, although molecular events may influence the pathogenetic mechanism of the phenomenon.

Original language	English (US)
Pages (from-to)	602-606
Number of pages	5
Journal	Head and Neck Pathology
Volume	16
Issue number	2
Early online date	Sep 1 2021
DOIs	https://doi.org/10.1007/s12105-021-01377-7
State	Published - Sep 1 2021

Bibliographical note

Funding Information:
The study was funded by the University of Minnesota Oral Pathology Research Fund (internal funding).

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Keywords

CD34
Collision tumor
Epithelial membrane antigen
Glut-1
Neurofibroma
Palate
Polymorphous adenocarcinoma

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s12105-021-01377-7

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title = "Polymorphous Adenocarcinoma, Low Grade Variant, Colliding with a Neurofibroma",

abstract = "Collision tumors, composed of two distinct benign or malignant neoplasms, are rarely reported in the oral cavity. We present a case of a 61-year-old female with an asymptomatic non-demarcated lump on the soft palate of unknown duration. An incisional biopsy revealed the presence of two neoplastic populations, a neurofibroma that was partially infiltrated by a polymorphous adenocarcinoma, low-grade variant. Total surgical excision was performed, with uneventful follow-up period. The development of collision tumors may be incidental, although molecular events may influence the pathogenetic mechanism of the phenomenon.",

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AU - Tosios, Konstantinos I.

AU - Lynch, Hannah Afwerke

AU - Uppgaard, Rachel

AU - Koutlas, Ioannis G.

N1 - Funding Information: The study was funded by the University of Minnesota Oral Pathology Research Fund (internal funding). Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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AB - Collision tumors, composed of two distinct benign or malignant neoplasms, are rarely reported in the oral cavity. We present a case of a 61-year-old female with an asymptomatic non-demarcated lump on the soft palate of unknown duration. An incisional biopsy revealed the presence of two neoplastic populations, a neurofibroma that was partially infiltrated by a polymorphous adenocarcinoma, low-grade variant. Total surgical excision was performed, with uneventful follow-up period. The development of collision tumors may be incidental, although molecular events may influence the pathogenetic mechanism of the phenomenon.

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Polymorphous Adenocarcinoma, Low Grade Variant, Colliding with a Neurofibroma

Abstract

Bibliographical note

Keywords

UN SDGs

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