Polydisperse tube diameters compromise multiple open tubular chromatographyw

D. K. Schisla, Hongbing Ding, P. W. Carr, E. L. Cussler

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


This article demonstrates that even 1% polydispersity in hollow‐fiber diameters can increase plate heights by as much as an order of magnitude. The demonstration includes an analytical extension of the Taylor‐Aris and the Golay dispersion theories, a numerical solution using the measured polydisperity, and successful predictions of the performance of different hollow‐fiber systems over a range of flow rates. All these results show that the effect of polydispersity can dominate column performance, especially in the region where the column efficiency is optimal.

Original languageEnglish (US)
Pages (from-to)946-953
Number of pages8
JournalAIChE Journal
Issue number6
StatePublished - Jun 1993


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