TY - JOUR
T1 - Polycystic ovary syndrome and ovulation induction
AU - Phipps, W. R.
PY - 2001/1/1
Y1 - 2001/1/1
N2 - Before initiating treatment to induce ovulation in cases of PCOS, an appropriate evaluation of the patient and her partner, based on individual considerations, is important to optimize outcome. For obese patients with PCOS, weight-loss measures should be pursued before pharmacologic treatment is initiated. For most patients, the pharmacologic agent of choice to induce ovulation is clomiphene citrate, alone or in combination with a glucocorticoid. Treatment with metformin, alone or in combination with clomiphene citrate, may also be beneficial. For patients not responsive to clomiphene citrate, injectable gonadotropin treatment is usually warranted, although, depending on individual circumstances, laparoscopic ovarian drilling may be appropriate.
AB - Before initiating treatment to induce ovulation in cases of PCOS, an appropriate evaluation of the patient and her partner, based on individual considerations, is important to optimize outcome. For obese patients with PCOS, weight-loss measures should be pursued before pharmacologic treatment is initiated. For most patients, the pharmacologic agent of choice to induce ovulation is clomiphene citrate, alone or in combination with a glucocorticoid. Treatment with metformin, alone or in combination with clomiphene citrate, may also be beneficial. For patients not responsive to clomiphene citrate, injectable gonadotropin treatment is usually warranted, although, depending on individual circumstances, laparoscopic ovarian drilling may be appropriate.
UR - http://www.scopus.com/inward/record.url?scp=0035081340&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035081340&partnerID=8YFLogxK
U2 - 10.1016/S0889-8545(05)70192-3
DO - 10.1016/S0889-8545(05)70192-3
M3 - Article
C2 - 11293001
AN - SCOPUS:0035081340
SN - 0889-8545
VL - 28
SP - 165
EP - 182
JO - Obstetrics and Gynecology Clinics of North America
JF - Obstetrics and Gynecology Clinics of North America
IS - 1
ER -