Polycystic ovary syndrome and ovulation induction

W. R. Phipps

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Before initiating treatment to induce ovulation in cases of PCOS, an appropriate evaluation of the patient and her partner, based on individual considerations, is important to optimize outcome. For obese patients with PCOS, weight-loss measures should be pursued before pharmacologic treatment is initiated. For most patients, the pharmacologic agent of choice to induce ovulation is clomiphene citrate, alone or in combination with a glucocorticoid. Treatment with metformin, alone or in combination with clomiphene citrate, may also be beneficial. For patients not responsive to clomiphene citrate, injectable gonadotropin treatment is usually warranted, although, depending on individual circumstances, laparoscopic ovarian drilling may be appropriate.

Original languageEnglish (US)
Pages (from-to)165-182
Number of pages18
JournalObstetrics and Gynecology Clinics of North America
Issue number1
StatePublished - Jan 1 2001


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