Pneumonia in HIV-exposed and Infected Children and Association With Malnutrition

Pui Ying Iroh Tam; Matthew O. Wiens; Jerome Kabakyenga; Julius Kiwanuka; Elias Kumbakumba; Peter P. Moschovis

doi:10.1097/INF.0000000000001971

Pneumonia in HIV-exposed and Infected Children and Association With Malnutrition

Pui Ying Iroh Tam, Matthew O. Wiens, Jerome Kabakyenga, Julius Kiwanuka, Elias Kumbakumba, Peter P. Moschovis

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We evaluated the association between HIV exposed-uninfected (HEU) status, malnutrition and risk of death in Ugandan children hospitalized with pneumonia. Both HIV exposure and infection were associated with lower anthropometric indices on univariate analysis, and mid-upper arm circumference was significantly associated with overall mortality (odds ratio (OR), 0.96) in a multivariable model. HIV infection (OR 5.0) but not HEU status was associated with overall mortality. Malnutrition may contribute to poor pneumonia outcomes among HIV-infected and HEU children requiring hospitalization.

Original language	English (US)
Pages (from-to)	1011-1013
Number of pages	3
Journal	The Pediatric infectious disease journal
Volume	37
Issue number	10
DOIs	https://doi.org/10.1097/INF.0000000000001971
State	Published - Oct 1 2018
Externally published	Yes

PubMed: MeSH publication types

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

UN SDGs

This output contributes to the following Sustainable Development Goal(s)

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10.1097/INF.0000000000001971

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119658

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abstract = "We evaluated the association between HIV exposed-uninfected (HEU) status, malnutrition and risk of death in Ugandan children hospitalized with pneumonia. Both HIV exposure and infection were associated with lower anthropometric indices on univariate analysis, and mid-upper arm circumference was significantly associated with overall mortality (odds ratio (OR), 0.96) in a multivariable model. HIV infection (OR 5.0) but not HEU status was associated with overall mortality. Malnutrition may contribute to poor pneumonia outcomes among HIV-infected and HEU children requiring hospitalization.",

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AU - Kumbakumba, Elias

AU - Moschovis, Peter P.

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