PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma

Branden A. Smeester, Nicholas J. Slipek, Emily J. Pomeroy, Kanut Laoharawee, Sara H. Osum, Alex T. Larsson, Kyle B. Williams, Natalie Stratton, Kenta Yamamoto, Joseph J. Peterson, Susan K. Rathe, Lauren J. Mills, Wendy A. Hudson, Margaret R. Crosby, Minjing Wang, Eric P. Rahrmann, Branden S. Moriarity, David A. Largaespada