Plasmacytoid myoepithelioma of the hard palate: Case report

Christina Efthymia Souliou, Fotios Tzermpos, Prokopios Argyris, Konstantinos Tosios

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3 Scopus citations


Background: Myoepitheliomas are uncommon salivary gland neoplasms consisting entirely or predominantly of cells with myoepithelial phenotype. They commonly involve the parotid gland and the minor salivary glands of the palate. Aim: A case of plasmacytoid myoepithelioma of the hard palate is described. Case description and results: A 55-year-old woman presented to her oral surgeon with a tumor on the hard palate. Microscopic examination showed a well-circumscribed but non-encapsulated tumor, consisting mostly of plasmacytoid cells in a loose fibrovascular stroma. Neoplastic myoepithelial cells showed immunoreactivity for S-100 protein, CK AE1/AE3 (Figure 5b), GFAP, calponin, and CD138/Syndecan-1. Total excision of the tumor under local anesthesia was performed and no recurrence was noted 14 months after treatment. Conclusions: Since plasmacytoid myoepithelioma is uncommon, minor salivary glands, its immunohistochemical features, management and prognosis should be further investigated.

Original languageEnglish (US)
Pages (from-to)152-156
Number of pages5
JournalActa Stomatologica Croatica
Issue number2
StatePublished - Jun 1 2017


  • Hard palate
  • Myoepithelioma
  • Pleomorphic adenoma
  • Salivary gland neoplasms


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